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In Niemann-Pick’s disease the following substrance accumulate in CNS in excess______________?

  • (A)  Glycerophosphatides
  • (B)  Phosphoinositides
  • (C)  Phosphosphingosides
  • (D)  Glycerosphingosides
Submitted By :Ali Uppal


Limiting factory for fatty acid synthesis_________________?

  • (A)  Aceto acetate synthetase
  • (B)  Acyl transferase
  • (C)  Acetyl CoA carboxylase
  • (D)  Biotin
Submitted By :Ali Uppal


NADPH is required for________________?

  • (A)  Gluconeogenesis
  • (B)  Glycolysis
  • (C)  Fatty acid synthesis
  • (D)  Glycogenolysis
Submitted By :Ali Uppal


Ketone body formation takes place in_______________?

  • (A)  Liver
  • (B)  Kidney
  • (C)  Spleen
  • (D)  Blood
Submitted By :Ali Uppal


Which of the following is not a ketone body______________?

  • (A)  Acetone
  • (B)  Acetic acid
  • (C)  Acetocetate
  • (D)  Beta hydroxybutyric acid
Submitted By :Ali Uppal


Which of the following organs cannot use ketone bodies_______________?

  • (A)  Brain
  • (B)  Liver
  • (C)  Kidney
  • (D)  Spleen
Submitted By :Ali Uppal


All are derived of cholesterol except________________?

  • (A)  Chenodeoxy cholic acid
  • (B)  Glycocholic acid
  • (C)  Testosterone
  • (D)  Cholecystokinin
Submitted By :Ali Uppal


The precursor of cholesterol synthesis is________________?

  • (A)  Acetic acid
  • (B)  Acetyl CoA
  • (C)  Oxalo acetic acid
  • (D)  Pyruvate
Submitted By :Ali Uppal


HMG-CoA is formed during metabolism of all except______________?

  • (A)  Cholesterol
  • (B)  Leucine
  • (C)  Ketone bodies
  • (D)  Bile acids
Submitted By :Ali Uppal


HMG CoA reductase is inhibited by_____________?

  • (A)  Clofibrate
  • (B)  Gemfibrosil
  • (C)  Lovastatin
  • (D)  cholestyramine
Submitted By :Ali Uppal