All of the following statements regarding biovailability of a drug are true except______________?
(A) It is the proportion (fraction) of unchanged drug that reaches the systemic circulation
(B) Biovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration
(C) Low oral biovailability always and necessarily mean poor absorption
(D) Biovailability can be determined from plasma concentration or urinary excretion data
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